Abstract EANA2024-13

In the quest for prolonged human habitation beyond Earth, sustaining essential biological processes poses a paramount challenge. This abstract outlines groundbreaking research focused on establishing and maintaining a cell bank in the distinctive microgravity environment of space, with a specific emphasis on stem cell biology. The investigation explores the intricacies of cultivating and preserving stem cells in space, unraveling potential applications and implications for the future of astrobiology and space exploration.

Our study represents a pioneering effort in the development of a state-of-the-art bioreactor system, specifically tailored to the challenges posed by extraterrestrial environments. This cutting-edge apparatus facilitates the cultivation and propagation of diverse stem cell types, ensuring their viability and functionality under reduced gravity conditions. Initial experimental ideas will underscore the success of cell proliferation and the maintenance of stem cell characteristics, emphasizing the remarkable adaptability of cellular systems to the space environment.

The future applications of space-optimized cell banking extend beyond immediate research objectives, encompassing addressing health concerns during prolonged space missions, advancing regenerative medicine, and laying the foundation for potential cellular-based life support systems in extraterrestrial colonies. Insights gained from this research may revolutionize our understanding of fundamental processes governing cellular life in space.

The basic design of our space-optimized cell bank features a modular bioreactor system equipped with cutting-edge environmental controls to simulate space conditions. This bioreactor integrates a closed-loop nutrient delivery system, real-time monitoring of cellular responses, and a compact, low-mass design to minimize resource requirements during space missions. Results from experiments not only highlight stem cell adaptability to space conditions but also offer crucial data for refining future space-based biological systems.

This research makes a significant contribution to the international discussion on space exploration and astrobiology. By focusing on the challenges of sustaining biological processes in space using stem cell biology, our work will establish a foundation for collaborative initiatives aimed at developing sustainable life support systems beyond Earth. The innovative technologies and insights presented in this study offer great potential for shaping the future of space exploration and enhancing our abilities for long-term human habitation in the cosmos.